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Commercially… CylanceProtect with FireEye HX, and ESET (or something that is leveraging AMSI) Gartner also recently published an article on Microsoft ATP changing the landscape.
Home use, MalwareBytes, CylanceProtect, ESET/SEP (mainly because of customization allowed)
And the obligatory FireFox w/NoScript, and make sure your using Sysmon.
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