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You can if the 4.0 module exposes what you need via COM. The 2.0 assembly can then use the object(s) via COM. A straight import is not possible though because of the .NET version mis-match though.
You can see more info on how to accomplish this here:
http://www.codeproject.com/Articles/204406/How-To-Use-a-NET-Based-DLL-From-NET-Based-Appl
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