Best Antivirus Engine

[!k-0t1c!]

If you're not doing a lot of nasty stuff, Prevx can be very effective at stopping threats. It's quite proactive and thus will stop most unknown and possibly malicious files from running, plus it's very good at cleaning up existing malware (that alone imo would justify its cost). If you're using the PC for active development or better yet for IT security research Prevx will get in your way far too much to tolerate it. In that case AVIRA + ClamAV for Windows (connected to Immunet) will be a pretty safe setup, if you keep your box properly patched and configured.