Best software protector: Themida or Enigma Protector?

[quosego]

Themida has been impossible, for now...

Hmmm as deathway also noted themida has not been impossible for quite some time.

VMprotect has no public devirtulaizer, but they exist. Obfuscation is also pretty lame there. It's antidebug I'd say is best of all these, however with the correct plugins you don't have to do anything to bypass.. And sunbeam documented this pretty well.

Noobyprotect is not often used and has some compatibility issues I noticed, at least in the crackme's released. Perhaps they're fixed by now. No experience with TTprotect, rarely used as far as I know.

Well the point is actually all have been defeated, though most are actually pretty good. Themida/enigma and VMprotect are the more commonly used ones, but they all have been defeated. There's simply no flawless protector out there. The above protectors will stop all newbies anyway so in that regard you're already good.